Systemic Lupus Erythematosus (SLE) explained, including pathophysiology, causes and a mnemonic for SLE symptoms (SOAP BRAIN MD). We also cover the EULAR / ACR diagnostic criteria for SLE, as well as SLE treatment. 

PDFs available at: https://rhesusmedicine.com/pages/rheumatology

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Timestamps 
0:00 What is SLE? (Systemic Lupus Erythematosus)
1:02 SLE Pathophysiology
3:08 SLE Causes
4:21 SLE Symptoms (SLE Mnemonic SOAP BRAIN MD)
7:13 SLE Diagnosis (EULAR & ACR criteria)
9:22 SLE Treatment

LINK TO MNEMONICS:
https://www.youtube.com/watch?v=p-XE7PiwGgE&list=PLGNSE_HvIV4t7a33bbHN1fq-j_tge0Gmp

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https://www.instagram.com/rhesusmedicine/

References

1. BMJ Best Practice (2025) Systemic lupus erythematosus – Symptoms, diagnosis and treatment. BMJ Best Practice. Available at: https://bestpractice.bmj.com/topics/en-gb/103
2. Lupus Foundation of America (n.d.) The history of lupus. Lupus Foundation of America. Available at: https://www.lupus.org/resources/the-history-of-lupus
3. EdRheum (n.d.) Systemic lupus erythematosus. EdRheum. Available at: https://edrheum.org/systemic-lupus/
4. MSD Manual Professional Edition (2025) Systemic lupus erythematosus (SLE). MSD Manual Professional Edition. Available at: https://www.msdmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/systemic-rheumatic-diseases/systemic-lupus-erythematosus-sle

Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.